ALPPS Surgery

CONTEXT

ALPPS stands for “Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy.” The goal of the technique is to perform a staged liver resection in two phases, promoting rapid liver hypertrophy. The technique was developed for the treatment of patients with multiple liver metastases from colorectal cancer.

PROCEDURE

The surgery is performed in two stages: first, one side of the liver is operated on, and after about four weeks, the other side is addressed. In the first surgery, all nodules on one side of the liver are removed, a branch of the portal vein, one of the blood vessels responsible for supplying the organ, is ligated, and the liver is partitioned (divided into two). After 7 to 14 days, there is significant hypertrophy of the side of the liver free of tumors, allowing for the second surgery and removal of the side with tumors, whose portal vein branch had been ligated.

Procedure

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